Article

Dietary isoleucine content defines the metabolic and molecular response to a Western diet

2024-06-03

Abstract excerpt

The amino acid composition of the diet has recently emerged as a critical regulator of metabolic health. Consumption of the branched-chain amino acid isoleucine is positively correlated with body mass index in humans, and reducing dietary levels of isoleucine rapidly improves the metabolic health of diet-induced obese male C57BL/6J mice. However, it is unknown how sex, strain, and dietary isoleucine intake may int...

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Literature Corpus work: 8a536d85-71fc-569c-bbe5-c5b392356737
DOI: 10.1101/2024.05.30.596340

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