Article
BMI1 promotes osteosarcoma proliferation and metastasis by repressing the transcription of SIK1
27 Mar 2022
Abstract excerpt
BACKGROUND: Osteosarcoma (OS) is the most common malignant tumor of bone, and the clinical efficacy of current treatments and associated survival rates need to be further improved by employing novel therapeutic strategies. Although various studies have shown that BMI1 protein is universally upregulated in OS cells and tissues, its specific role and underlying mechanism have not yet been fully explored. METHODS:...
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