Article

Chronic intestinal immune activation reveals separable impacts of inflammation and barrier loss on hallmarks of ageing

2025-08-15

Abstract excerpt

Inflammaging is considered a driver of age-associated pathology across tissues. Similarly, intestinal permeability is a feature of ageing and underlies a range of inflammatory and age-related diseases. Increased intestinal permeability has been described as both a cause and a consequence of inflammation. Both intestinal permeability and inflammation are closely associated with microbial dysbiosis, epithelial dyspl...

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Literature Corpus work: 8a0f95d4-cc4d-5099-b7bc-50581e0c883e
DOI: 10.1101/2025.08.11.669650

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