Article

Comprehensive Bioinformatic Analysis for Identification of Crucial Genes and Signaling Transduction Pathways in Head and Neck Squamous Cell Carcinoma

2024-02-15

Abstract excerpt

<title>Abstract</title> <p>Head and neck squamous cell carcinoma (HNSCC) is a prevalent global cancer, ranking sixth in incidence. Investigating the molecular basis of tumorigenesis and metastasis is crucial for early detection and effective treatment. Our study utilized three gene expression profile datasets (GSE6791, GSE29330, and GSE58911) to identify co-up or down-regulated differentially expressed genes (DEG...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 87de8e3d-1e00-55b2-9df2-0c9eee53f10a
DOI: 10.21203/rs.3.rs-3912796/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Bioinformatic Analysis for Identification of Crucial Genes and Signaling Transduction Pathways in Head and Neck Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-3912796/v1Read

Identification and analysis of genes associated with head and neck squamous cell carcinoma by integrated bioinformatics methodsSemantic proximity Read

SPP1 and FN1 are significant gene biomarkers of tongue squamous cell carcinomaSemantic proximity Read

Identification of Hub Genes Associated With Development of Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatics AnalysisSemantic proximity Read

Identiﬁcation of Key Genes and Pathways in Tongue Squamous Cell Carcinoma Using Bioinformatics AnalysisSemantic proximity Read

Co-expression Network Identification and Clinical Prognostic Evaluation of Hub Genes in Head and Neck Squamous Cell CarcinomaSemantic proximity Read

The relevance between the immune response-related gene module and clinical traits in head and neck squamous cell carcinomaSemantic proximity Read

SPINK5 is a Prognostic Biomarker Associated With the Progression and Prognosis of Laryngeal Squamous Cell Carcinoma Identified by Weighted Gene Co-Expression Network AnalysisSemantic proximity Read

Identity of MMP1 and its effects on tumor progression in head and neck squamous cell carcinomaSemantic proximity Read

Identification of a Novel Epithelial–Mesenchymal Transition Gene Signature Predicting Survival in Patients With HNSCCSemantic proximity Read

Application of weighted gene co-expression network analysis to explore potential prognostic markers of head and neck squamous cell carcinomaSemantic proximity Read

Common gene signatures and key pathways in hypopharyngeal and esophageal squamous cell carcinomaSemantic proximity Read

Screening and identification of significant genes in esophageal squamous cell carcinoma by bioinformatical analysisSemantic proximity Read