Article

Clustering by phenotype and genome-wide association study in autism

2019-04-22

Abstract excerpt

<h4>Background</h4> Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous characteristics. A simulation study demonstrated that attempts to categorize patients with a complex disease into more homogeneous subgroups could have more power to elucidate hidden heritability. <h4>Methods</h4> We conducted cluster analyses using the k-means algorithm with a cluster number of 15 based on phenot...

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Literature Corpus work: 89b8ab5b-bf34-5663-bc3a-29675af6ffe6
DOI: 10.1101/614958

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