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Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families.

Genes - 18 May 2021

Al-Sarraj Yasser, Al-Dous Eman, Taha Rowaida Z, Ahram Dina, Alshaban Fouad, Tolfat Mohammed, El-Shanti Hatem, Albagha Omar M E

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by abnormalities in language and social communication with substantial clinical heterogeneity. Genetic factors play an important role in ASD with heritability estimated between 70% to 80%. Genome-wide association studies (GWAS) have identified multiple loci associated with ASD. However, most studies were performed on European populations...

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Identifiers

PMID: 34069769
DOI: 10.3390/genes12050761
PMCID: PMC8157263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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