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Article

Alcohol exposure promotes MMP9-mediated CCN1 cleavage in esophageal adenocarcinoma

2025-03-18

Abstract excerpt

<h4>Background: </h4> Alcohol consumption has been a risk factor for more than 200 diseases, including esophageal cancer. CCN1, a matricellular protein, is highly expressed in esophageal squamous cell carcinoma (ESCC) but is barely detectable in esophageal adenocarcinoma (EAC). Alcohol consumption has been identified as a major contributor to ESCC development, but its role in EAC is uncertain. This study investiga...

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Literature Corpus work
89b4a8a3-0496-5c9f-aeb9-099592372868
DOI
10.22541/au.174229761.17147740/v1
Open publication

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