Article

Expression of HPV oncogenes from a single integration site in cervical cancer cell lines

2020-06-27

Abstract excerpt

Integration of a virus genome into human chromosomal DNA is critical in viral carcinogenesis. In this report, we discovered that virus-host fusion transcripts are characteristically originated mainly from a single integration site in three cervical cancer cell lines, CaSki and SiHa cells with multiple HPV16 DNA integration sites and HeLa cells with multiple HPV18 DNA integration sites. The host genomic elements su...

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Literature Corpus work: 89ae40b5-9893-5e3e-b308-33ced6aa5d60
DOI: 10.1101/2020.06.25.171959

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