Article

Ultrastructural and Histological Cryopreservation of Mammalian Brains by Vitrification

2026-02-01

Abstract excerpt

Studies of whole brain cryopreservation are rare but are potentially important for a variety of applications. It has been demonstrated that ultrastructure in whole rabbit and pig brains can be cryopreserved by vitrification (ice-free cryopreservation) after prior aldehyde fixation, but fixation limits the range of studies that can be done by neurobiologists, including studies that depend upon general molecular int...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 897e68e7-16d8-58bf-b6bb-41f2c4e669a2
DOI: 10.64898/2026.01.28.702375

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultrastructural and Histological Cryopreservation of Mammalian Brains by VitrificationDOI 10.64898/2026.01.28.702375Read

Aldehyde-based cryopreservation of whole brainsSemantic proximity Read

Cryopreservation of Human Cortical Organoids Using VitrificationSemantic proximity Read

Postmortem changes in brain cell structure: a reviewSemantic proximity Read

Micromanaging freeze tolerance: the biogenesis and regulation of neuroprotective microRNAs in frozen brainsSemantic proximity Read

Improved membrane preservation of flavivirus-infected cells with cryosectioningSemantic proximity Read

Native ultrastructure of fresh human brain vitrified directly from autopsy revealed by cryo-electron tomography with cryo-plasma focused ion beam millingSemantic proximity Read

Cryo-FIB workflow for imaging brain tissue via <i>in situ</i> cryo-electron microscopySemantic proximity Read

Vitrification of Domestic Cat Oocytes – Effect on Viability and Integrity of Subcellular StructuresSemantic proximity Read

Increasing dehydration of human cleavage-stage embryos prior to slow cooling significantly increases cryosurvivalSemantic proximity Read

Spatiotemporal trajectories of formaldehyde fixation effects on quantitative MRI in postmortem human brainsSemantic proximity Read

New neurons in old brains: A cautionary tale for the analysis of neurogenesis in post-mortem tissueSemantic proximity Read

Cryopreserved GABAergic neurons in cultures of rat cerebral cortex and mesencephalon: a comparative morphometric study with anti-GABA antibodies.Semantic proximity Read