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Metabolomic analysis of diverse mice reveals hepatic arginase-1 as source of plasma arginase in <i>Plasmodium chabaudi</i> infection

2021-06-13

Abstract excerpt

Infections disrupt host metabolism, but the factors that dictate the nature and magnitude of metabolic change are incompletely characterized. To determine how host metabolism changes in relation to disease severity in murine malaria, we performed plasma metabolomics on eight Plasmodium chabaudi -infected mouse strains with diverse disease phenotypes. We identified plasma metabolic biomarkers for both the nature a...

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Literature Corpus work
897aebfd-caea-5ba5-a3a4-a96379d3be2d
DOI
10.1101/2021.06.11.448167
Open publication

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Metabolomic analysis of diverse mice reveals hepatic arginase-1 as source of plasma arginase in <i>Plasmodium chabaudi</i> infectionDOI 10.1101/2021.06.11.448167
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