Article

MicroRNA-sensing plasmid system for dynamic control of functional ion channel expression

2026-02-06

Abstract excerpt

Gene therapy offers the potential for long-term treatment or cures for a range of chronic diseases. However, permanent gene therapy expression may not be desirable. Efforts have been made to create systems which can be switched on/off by stimuli including light, designer drugs, or cellular contexts such as increased electrical activity. Here, we designed a novel plasmid system in which ion channel expression, and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8931242a-f0e8-5177-8edd-f906d962a1bd
DOI: 10.64898/2026.02.04.703753

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

MicroRNA-sensing plasmid system for dynamic control of functional ion channel expressionDOI 10.64898/2026.02.04.703753Read

An orthogonal Cro/O <sub>R</sub> 3 binary system for targeted gene expressionSemantic proximity Read

Optimized riboswitch-regulated AAV vector for VEGF-B gene therapySemantic proximity Read

Clinical applicability of optogenetic gene regulationSemantic proximity Read

RNAi-mediated rheostat for dynamic control of AAV-delivered transgenesSemantic proximity Read

In ovo electroporation of miRNA-based-plasmids to investigate gene function in the developing neural tube.Semantic proximity Read

Enhanced ouabain resistance gene as a eukaryotic selection marker.Semantic proximity Read

Viral and Non-Viral Systems to Deliver Gene Therapeutics to Clinical TargetsSemantic proximity Read

The Current Status of Gene Therapy for the Treatment of CancerSemantic proximity Read