Article

Targeting circadian transcriptional programs through a cis-regulatory mechanism in triple negative breast cancer

2024-04-29

Abstract excerpt

Circadian clock genes are emerging targets in many types of cancer, but their mechanistic contributions to tumor progression are still largely unknown. This makes it challenging to stratify patient populations and develop corresponding treatments. In this work, we show that in breast cancer, the disrupted expression of circadian genes has the potential to serve as biomarkers. We also show that the master circadian...

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Identifiers and source

Literature Corpus work: 891c5b01-de7c-5508-8a2c-34dc9524ec22
DOI: 10.1101/2024.04.26.590360

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