Article

Soluble and cell-based markers of immune checkpoint inhibitor associated nephritis

2022-10-17

Abstract excerpt

<h4>Background</h4> Non-invasive biomarkers of immune checkpoint inhibitor-associated acute tubulointerstitial nephritis (ICI-nephritis) are urgently needed. Because ICIs block immune checkpoint pathways that include cytotoxic T lymphocyte antigen 4 (CTLA4), we hypothesized that biomarkers of immune dysregulation previously defined in patients with congenital CTLA4 deficiency, including elevated soluble interleuki...

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Literature Corpus work: 88c7e48e-0bb8-524e-966a-56fafc39b338
DOI: 10.1101/2022.10.13.22280966

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