Back to search

Article

DNMT1 has prognostic values in HER2-positive breast cancer

2022-08-09

Abstract excerpt

<h4>Background: </h4> Interleukin-6 (IL-6) was found to induce aberrant methylation in critical genes involved in insulin signaling and angiogenesis in humans, presumably due to protein stabilization of DNA methyltransferases. Whether IL-6 and DNMT1 impact breast cancer (BC) prognosis remains unknown. Methods TIMER2.0 web server was used for comprehensive analysis from TCGA. Associations between DNMT1 and IL-6 in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
88b7763a-8a73-5a00-902e-4b2e1e2390f6
DOI
10.21203/rs.3.rs-1929732/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 11 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
DNMT1 has prognostic values in HER2-positive breast cancerDOI 10.21203/rs.3.rs-1929732/v1
Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology.Semantic proximity
Interleukin-6–mediated epigenetic control of the VEGFR2 gene induces disorganized angiogenesis in human breast tumorsSemantic proximity
Prognostic Value of CMTM6 Expression in Breast CancerSemantic proximity
Bioinformatics Analysis the Characteristics and Correlation of m6A Methylation in Breast Cancer ProgressionSemantic proximity
CTHRC1 is a Potential Prognostic Biomarker and Correlated with Macrophage Infiltration in Breast CancerSemantic proximity
DNMT1 rs2228611, rs2228612 and DNMT3A rs2276598, rs752208 Polymorphisms and Their Association with Breast Cancer Phenotype and Prognosis.Semantic proximity
DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood.Semantic proximity
ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6BSemantic proximity
HTRA1 expression is associated with immune-cell infiltration and survival in breast cancerSemantic proximity
Decelerated DNA methylation age predicts poor prognosis of breast cancerSemantic proximity
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General AnesthesiaSemantic proximity
Select a neighboring publication to make it the new centre.