Article

Transposable elements regulate thymus development and function

2023-07-14

Abstract excerpt

Transposable elements (TE) are repetitive sequences representing ∼45% of the human and mouse genomes and are highly expressed by medullary thymic epithelial cells (mTEC). In this study, we investigated the role of TEs on T-cell development in the thymus. We performed multi-omic analyses of TEs in human and mouse thymic cells to elucidate their role in T cell development. We report that TE expression in the human t...

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Literature Corpus work: 889d6e23-7ec6-57c5-8455-0344ba7a0cc7
DOI: 10.1101/2023.07.12.548732

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