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Sirt1, as a Potential Prognosis Marker in Renal Clear Cell Carcinoma, regulates lipid metabolism and immune infiltration

2023-07-20

Abstract excerpt

Renal clear cell carcinoma (ccRCC) is a malignancy with a dismal prognosis, characterized by the accumulation of fat and glycogen. Sirt1 is a deacetylase that regulates lipid metabolism. In this study, we collected tumor and paracancer tissues from 386 ccRCC patients and followed their prognosis over an extended period. Immunohistochemistry was used to get the expression of Sirt1 in these tissues, and the differen...

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Literature Corpus work
0470e61b-9231-5597-bd48-08d9f7555dfe
DOI
10.21203/rs.3.rs-3159727/v1
Open publication

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