Article

Suppression of AQP7 is Crucial for Proliferation and Lipid Metabolism in ccRCC

2024-03-13

Abstract excerpt

<h4>Background: </h4> It is well-established that reprogramming of lipid metabolism is a feature of clear cell renal cell carcinoma (ccRCC), which also acts as a driving force in oncogenesis induced by hypoxia-inducible factors (HIFs) in ccRCC. Aquaporin 7 (AQP7), a channel facilitates glycerol to pass through the membrane and induces a decrease in triglycerides (TGs) and glycerol in adipocytes. However, whether A...

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Literature Corpus work: 7a108ad2-6b26-5f15-aaca-a6b3d5184fcd
DOI: 10.21203/rs.3.rs-4058796/v1

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