Article

Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions

2015-06-11

Abstract excerpt

Diphencyprone (DPCP) is a hapten that causes delayed-type hypersensitivity (DTH) reactions in human skin, and is used as a topical therapeutic for alopecia areata, warts, and cutaneous melanoma metastases. We examined peak DTH reactions induced by DPCP (3 days post-challenge) by comprehensive gene expression and histological analysis. To better understand how these DTH reactions naturally resolve, we compared ou...

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Literature Corpus work: 87c69f55-baa0-5eff-8dae-ec6ebe6ba7b9
DOI: 10.12688/f1000research.6581.1

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