Article
A distinct psoriasis-atopic dermatitis overlapping phenotype in adults with dual type 2 and type 3 immune features and favorable response to Janus kinase 1 inhibition.
Journal of the American Academy of Dermatology - 1 Sept 2026
Chen Mengjiao, Shen Chen, Chen Chun-Bing, Liu Yeqiang, Huang Yu-Huei, Lu Chun-Wei, Chung-Yee Hui Rosaline, Su Chih-Yu, Wang Chuang-Wei, Chung Wen-Hung, Tao Juan
Abstract excerpt
BACKGROUND: Patients exhibiting overlapping histopathologic features of psoriasis (Pso) and atopic dermatitis (AD) present a diagnostic and therapeutic challenge. OBJECTIVES: To delineate the clinicopathological and immunologic portrait of psoriasis-atopic dermatitis overlapping (Pso-Ec) for integrated diagnosis and therapeutic decision-making. METHODS: We conducted a 2-center prospective study comparing 30...
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