Article

Intravenous immunoglobulin has epigenetic, ribosomal, and immune effects in Paediatric Acute-Onset Neuropsychiatric Syndrome

2025-03-30

Abstract excerpt

Paediatric acute-onset neuropsychiatric syndrome (PANS) is characterised by infection-provoked abrupt and dramatic onset of obsessive compulsive disorder (OCD) or eating restriction, along with neurodevelopmental regression. Although the aetiology of PANS remains uncertain, due to a prevailing neuroimmune hypothesis some children receive the immune modulator intravenous immunoglobulin (IVIg). Using single-cell RNA...

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Literature Corpus work: 01e61d15-6416-5a93-af4f-9f9ce5b57012
DOI: 10.1101/2025.03.27.25324808

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