Article
Estrogen Receptor Expression in DICER1-related Lesions is Associated With the Presence of Cystic Components.
The American journal of surgical pathology - 1 Jun 2024
Thorner Paul Scott, Chong Anne-Laure, Apellaniz-Ruiz Maria, Benlimame Naciba, Marrano Paula, Brimo Fadi, Shuangshoti Somruetai, Shuangshoti Shanop, Foulkes William D
Abstract excerpt
DICER1 tumor predisposition syndrome results from pathogenic variants in DICER1 and is associated with a variety of benign and malignant lesions, typically involving kidney, lung, and female reproductive system. Over 70% of sarcomas in DICER1 tumor predisposition syndrome occur in females. Notably, pediatric cystic nephroma (pCN), a classic DICER1 tumor predisposition syndrome lesion, shows estrogen receptor (ER)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.