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Article

Role of long noncoding RNAs in malignant disease (Review)

23 Dec 2015

Abstract excerpt

Long noncoding RNAs (lncRNAs) are endogenous transcribed RNA molecules without protein-coding potential, ranging between 200 and 100,000 nt in length. LncRNAs regulate the expression of specific genes in several ways, including guiding chromatin-remodeling, and affecting splicing, transcription or translation. The mutations and dysregulation of lncRNAs have been found to be important in various human diseases,...

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PMID: 26708950
DOI: 10.3892/mmr.2015.4711

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