Article

Adverse outcomes in SARS-CoV-2 infections are associated with a combination of variant genotypes at two loci in the APOL1 gene: a UK Biobank study

2021-11-02

Abstract excerpt

Risk of hospitalisation or death from COVID-19 in the UK is disproportionately high in people of African ancestry. Two APOL1 haplotypes (G1 and G2) found at high frequency only in populations of African descent are associated with increased risk of non-communicable and infectious diseases. Here, we test the hypothesis that adverse COVID-19 outcomes are also associated with these APOL1 high-risk variants. Within 9,...

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Literature Corpus work: 877ddbac-5c13-55f6-9af4-5bcedc4ec07c
DOI: 10.1101/2021.11.02.21265755

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