Article

Exogene: A performant workflow for detecting viral integrations from paired-end next-generation sequencing data

2021-04-19

Abstract excerpt

The integration of viruses into the human genome is known to be associated with tumorigenesis in many cancers, but the accurate detection of integration breakpoints from short read sequencing data is made difficult by human-viral homologies, viral genome heterogeneity, coverage limitations, and other factors. To address this, we present Exogene, a sensitive and efficient workflow for detecting viral integrations f...

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Literature Corpus work: 86c09fc4-3faf-5c38-81f3-dcdbc278d8ca
DOI: 10.1101/2021.04.19.440427

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