Article

Increased sampling and intra-complex homologies favor vertical over horizontal inheritance of the Dam1 complex

2022-10-04

Abstract excerpt

Kinetochores connect chromosomes to spindle microtubules to ensure their correct segregation during cell division. Kinetochores of human and yeast are largely homologous, their ability to track depolymerizing microtubules however is carried out by the non-homologous complexes Ska1-C and Dam1-C, respectively. We previously reported the unique anti-correlating phylogenetic profiles of Dam1-C and Ska-C found amongst...

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Literature Corpus work: 8639b64d-3d3a-5c88-972c-dde253dd1530
DOI: 10.1101/2022.10.04.510763

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