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Targets of the Tumor Suppressor <i>miR-200</i> in Regulation of the Epithelial–Mesenchymal Transition in Cancer

11 Oct 2011

Abstract excerpt

The microRNA-200 (miR-200) family restricts epithelial-mesenchymal transition (EMT) and metastasis in tumor cell lines derived from mice that develop metastatic lung adenocarcinoma. To determine the mechanisms responsible for EMT and metastasis regulated by this microRNA, we conducted a global liquid chromatography/tandem mass spectrometry analysis to compare metastatic and nonmetastatic murine lung...

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PMID: 21987723
DOI: 10.1158/0008-5472.can-11-0964

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