Article

Association of Bassoon (BSN) Gene Mutations with Gait and Motor Impairments in Parkinson's Disease

2025-08-12

Abstract excerpt

<h4>Introduction: </h4> Parkinson's Disease (PD) features debilitating motor symptoms, particularly gait and balance impairments inadequately managed by current therapies. Bassoon (BSN), a presynaptic active zone organizer, has been implicated in various neurological disorders. Here, we evaluate the impact of rare BSN mutations on motor symptoms in PD patients. Methods Our study included 110 PD patients carrying B...

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Literature Corpus work: 8597c83b-1d3f-5869-82c2-21fed4ac7e1d
DOI: 10.1101/2025.08.10.25333397

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