Article
Association of Bassoon (BSN) Gene Mutations With Gait and Motor Impairments in Parkinson's Disease.
The European journal of neuroscience - 1 Mar 2026
Kukkle Prashanth Lingappa, Panikkaveettil Kaladiyil Ahamed, Geetha Thenral S, Menon Ramesh, Kandadai Rukmini Mridula, Goyal Vinay, Desai Soaham Dilip, Joshi Deepika, Kumar Hrishikesh, Wadia Pettarusup M, Mukherjee Adreesh, Kumar Niraj, Mehta Sahil, Chargulla Sandeep, Murugan Shaktivel, Shah Heli S, Paramanandam Vijayshankar, Chandarana Mitesh, Yadav Ravi, Dhamija Rajinder K, Pal Pramod Kumar, Biswas Atanu, Gupta Ravi, Borgohain Rupam, Ramprasad Vedam L
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative syndrome with diverse biological drivers, where gait and balance dysfunction remain among the most disabling and least understood symptoms. Bassoon (BSN), a presynaptic active-zone organizer, has been implicated in various parkinsonian disorders. Here, we report the impact of BSN mutations on motor symptoms, especially gait-related symptoms, in PD patients. Our...
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