Article

The genetic drivers of juvenile, young, and early-onset Parkinson’s Disease in India

2023-06-22

Abstract excerpt

<h4>Background</h4> Recent studies have advanced our understanding of the genetic drivers of Parkinson’s Disease (PD). Rare variants in more than 20 genes are considered causal for PD, and the latest PD GWAS study identified 90 independent risk loci. However, there remains a gap in our understanding of PD genetics outside of the European populations in which the vast majority of these studies were focused. <h4>Obj...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5be213b9-a5de-5abb-bd93-dffee047f357
DOI: 10.1101/2023.06.18.23291407

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The genetic drivers of juvenile, young, and early-onset Parkinson’s Disease in IndiaDOI 10.1101/2023.06.18.23291407Read

The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India.Semantic proximity Read

Whole-genome sequencing of 197 cases with Parkinson’s Disease reveals novel pathogenic variants in the Indian populationSemantic proximity Read

Novel and reported variants in Parkinson's disease genes confer high disease burden among Indians.Semantic proximity Read

Deciphering the Genetic Architecture of Parkinson’s Disease in IndiaSemantic proximity Read

Genome-Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson's Disease Patients from India.Semantic proximity Read

Estimated genetics prevalence of early-onset Parkinson’s disease caused by<i>PRKN</i>mutationsSemantic proximity Read

Genomic profile of Parkinson's disease in Asians.Semantic proximity Read

Recalling the pathology of Parkinson's disease; lacking exact figure of prevalence and genetic evidence in Asia with an alarming outcome: A time to step-up.Semantic proximity Read

Large-scale genetic characterization of Parkinson’s disease in the African and African admixed populationsSemantic proximity Read

Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.Semantic proximity Read

Genetic characterization of Parkinson’s Disease in a Chilean cohortSemantic proximity Read

A genome-wide association study of young onset Parkinson’s disease in European ancestrySemantic proximity Read