Back to search

Article

Clinical Validation of Optical Genome Mapping for the Detection of Structural Variations in Hematological Malignancies

2022-12-29

Abstract excerpt

Structural variations (SVs) play a key role in the pathogenicity of hematological malignancies. Standard-of-care (SOC) methods such as karyotyping and fluorescence in situ hybridization (FISH), employed globally for the past three decades have significant limitations in the resolution or the number of recurrent aberrations that can be simultaneously assessed, respectively. Next-generation sequencing (NGS) based te...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8e778137-38cc-59be-8798-f1a50705a996
DOI
10.1101/2022.12.27.22283973
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Clinical Validation of Optical Genome Mapping for the Detection of Structural Variations in Hematological MalignanciesDOI 10.1101/2022.12.27.22283973
Analytic Validation of Optical Genome Mapping in Hematological MalignanciesSemantic proximity
Optical Genome Mapping: Clinical Validation and Diagnostic Utility for Enhanced Cytogenomic Analysis of Hematological NeoplasmsSemantic proximity
Application of Optical Genome Mapping to the Risk Stratification and Treatment Optimization of Hematologic DiseasesSemantic proximity
Clinical Validation and Diagnostic Utility of Optical Genome Mapping for Enhanced Cytogenomic Analysis of Hematological NeoplasmsSemantic proximity
Feasibility of Optical Genome Mapping in Cytogenetic Diagnostics of Hematological Neoplasms: A New Way to Look at DNASemantic proximity
Optical Genome Mapping improves detection and streamlines analysis of structural variants in myeloid neoplasmsSemantic proximity
Optical Genome Mapping: A New Tool for Cytogenomic AnalysisSemantic proximity
Clinical Utility of Optical Genome Mapping as an Additional Tool in a Standard Cytogenetic Workup in Hematological MalignanciesSemantic proximity
Optical Genome Mapping for Cytogenetic Diagnostics in AMLSemantic proximity
Optical genome mapping for structural variation analysis in hematologic malignanciesSemantic proximity
Genomic structural variants analysis in leukemia by a novel cytogenetic technique: Optical genome mappingSemantic proximity
Exploring the Potential of Optical Genome Mapping in the Diagnosis and Prognosis of Soft Tissue and Bone TumorsSemantic proximity
Select a neighboring publication to make it the new centre.