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<i>In silico</i> analysis of SNPs in human phosphofructokinase, Muscle ( <i>PFKM</i> ) gene: An apparent therapeutic target of aerobic glycolysis and cancer

2020-05-29

Abstract excerpt

<h4>ABSTRACT</h4> Phosphofructokinase, muscle (PFKM), a key glycolytic regulatory enzyme is a potential target for cancer therapeutic studies accredited to the employed inefficient phenomenon known as Warburg effect. PFKM is encoded by PFKM gene located at chromosome 12q13.11. Single nucleotide polymorphisms (SNPs) are known to profoundly affect gene expression and protein function. Therefore, the first attempt...

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Literature Corpus work
8531f80b-9de1-5bcd-a28d-c1d4e65a3df5
DOI
10.1101/2020.05.27.118653
Open publication

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