Article

IL-22 hinders antiviral T cell responses and exacerbates neurological disorders in ZIKV-infected immunocompetent neonatal mice

2020-06-02

Abstract excerpt

<title>Abstract</title> <p>Background The Zika virus (ZIKV) outbreak that occurred in multiple countries was linked to increased risk of neurological disorders and congenital defects. However, host immunity and immune-mediated pathogenesis in ZIKV infection are not well understood. Interleukin-22 (IL-22) is a crucial cytokine for regulating host immunity in infectious diseases. Whether IL-22 plays a role in ZIKV...

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Literature Corpus work: 850f04b7-d7d7-5d81-a30f-fcd3f111af50
DOI: 10.21203/rs.3.rs-31941/v1

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