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Zika virus inhibits cell death by inhibiting the expression of NLRP3 and A20

20 Feb 2025

Abstract excerpt

Zika virus (ZIKV) is associated with microcephaly in neonates and neurological disorders in adults. Chronic ZIKV infection has been identified in the testes, indicating that the virus can lead to prolonged illness, yet its pathogenesis remains poorly understood. Here, we found that ZIKV infection does not induce significant cell death in mouse macrophages despite the critical role that cell death plays in the...

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PMID: 39976465
DOI: 10.1128/jvi.01980-24

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