Article

Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancer

2017-12-18

Abstract excerpt

The human papillomavirus (HPV) is present in a significant fraction of head-and-neck squamous cell cancer (HNSCC). However, a comprehensive understanding of disease progression profiles comparing HPV+ and HPV- HNSCC cases is still lacking. The main goal of this study was to identify distinct co-expression patterns between HPV+ and HPV- HNSCC and to provide insights into potential regulatory mechanisms/effects (suc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 84bcf00c-9783-5844-b7ce-56e0a1627a66
DOI: 10.1101/236133

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancerDOI 10.1101/236133Read

Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancerSemantic proximity Read

Comparative analysis of HPV-Human Protein Interaction Networks in Oropharyngeal and Oral Squamous cell carcinomasSemantic proximity Read

The relevance between the immune response-related gene module and clinical traits in head and neck squamous cell carcinomaSemantic proximity Read

Novel Genomic Biomarker Candidates for Cervical Cancer As Identified by Differential Co-Expression Network AnalysisSemantic proximity Read

Network-Based Predictors of Progression in Head and Neck Squamous Cell CarcinomaSemantic proximity Read

SPINK5 is a Prognostic Biomarker Associated With the Progression and Prognosis of Laryngeal Squamous Cell Carcinoma Identified by Weighted Gene Co-Expression Network AnalysisSemantic proximity Read

Novel insights into head and neck cancer using next-generation "omic" technologies.Semantic proximity Read

A Systems Biology Approach to Unveil Shared Therapeutic Targets and Pathological Pathways Across Major Human CancersSemantic proximity Read

Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesisSemantic proximity Read

HPV16 Status Predicts Differential Interactome in Head and Neck Squamous Cell Carcinoma: Potential Prognostic Biomarkers and Therapeutics in Framework of 3P MedicineSemantic proximity Read

Application of weighted gene co-expression network analysis to explore potential prognostic markers of head and neck squamous cell carcinomaSemantic proximity Read

Subtypes of HPV-Positive Head and Neck Cancers Are Associated with HPV Characteristics, Copy Number Alterations, PIK3CA Mutation, and Pathway Signatures.Semantic proximity Read