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Article

Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesis

1 Sept 2018

Abstract excerpt

Purpose: Oral squamous cell carcinoma (OSCC) is one of the most common malignant diseases worldwide, yet its molecular mechanisms are largely unknown. We aimed to construct gene co-expression networks to identify key modules and hub genes involved in the pathogenesis of OSCC. Patients and methods: We used dataset GSE30784 to construct co-expression networks by weighted gene co-expression network analysis (WGCNA)....

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PMID: 30275705
DOI: 10.2147/ott.s171791

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