Article

Targeting the latent human cytomegalovirus reservoir with virus specific nanobodies

2020-05-13

Abstract excerpt

Latent reservoirs of viral pathogens are significant barriers to eradication of these viruses. During latency, herpesviruses maintain their genome, with little gene expression, making latent infections refractory to current treatments targeting viral replication. In the case of human cytomegalovirus (HCMV), sporadic reactivation events are well controlled by the immune system. However, in immunocompromised or immu...

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Literature Corpus work: 842884de-e28e-5767-86c9-347c14f187f2
DOI: 10.1101/2020.05.12.071860

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