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Article

Increased of Fascin1 and Pak1 expression enhances age-associated B cell actin cytoskeleton remodeling

2023-03-13

Abstract excerpt

<h4>Background: </h4> An atypical B cell subset of age-associated B cells (ABCs) accumulate with age in mice and humans. ABCs acquire the ability to secrete antibodies and inflammatory cytokines in response to TLR7 and TLR9, and present antigens to T cells more efficiently than follicular (FO) B cells, which promotes the development of pathogenic phenotypes in aged individuals. <h4>Results: </h4>: In this study,...

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Literature Corpus work
841e6f7d-375f-5e51-a2b8-7c61cba24cc5
DOI
10.21203/rs.3.rs-2659669/v1
Open publication

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Increased of Fascin1 and Pak1 expression enhances age-associated B cell actin cytoskeleton remodelingDOI 10.21203/rs.3.rs-2659669/v1
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