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Article

Method Validation for Extraction of DNA from Human Stool Samples for Downstream Microbiome Analysis

30 Jan 2020

Abstract excerpt

Background: A formal method validation for biospecimen processing in the context of accreditation in laboratories and biobanks is lacking. A previously optimized stool processing protocol was validated for fitness-for-purpose for downstream microbiome analysis. Materials and Methods: DNA extraction from human stool was validated with various collection tubes, stabilizing solutions and storage conditions in terms...

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Identifiers

PMID: 31999474
DOI: 10.1089/bio.2019.0112

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