Article

Synthesizing multidimensional clinical profiles from published Kaplan–Meier images

2026-03-19

Abstract excerpt

<h4>ABSTRACT</h4> Strict privacy regulations restrict access to individual-level clinical trial data, confining secondary evidence synthesis to isolated one-dimensional Kaplan-Meier summaries. Inferring unreported joint distributions from these independent marginals constitutes an ill-posed inverse problem that limits multivariable precision oncology. Conventional algorithms default to the maximum entropy (MaxEnt...

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Literature Corpus work: 83d2a75d-43ee-53a7-8ade-a7d3b392f59d
DOI: 10.64898/2026.03.17.26348584

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