Article

External Control Arm with Synthetic Real-world Data for Comparative Oncology using Single Trial Arm Evidence (ECLIPSE): A Case Study using Lung-MAP S1400I

2024-09-11

Abstract excerpt

2. Single-arm trials supplemented with external comparator arm(s) (ECA) derived from real-world data are sometimes used when randomized trials are infeasible. However, due to data sharing restrictions, privacy/security concerns, or for logistical reasons, patient-level real-world data may not be available to researchers for analysis. Instead, it may be possible to use generative models to construct synthetic data...

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Literature Corpus work: 782d5ec2-d8b9-5f04-b5f5-5ad8a297dcb4
DOI: 10.1101/2024.09.10.24313417

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