Article

A Kaplan–Meier point picker with genetic optimization enables constraint-rich individual patient data reconstruction for multicenter meta-analysis

2026-06-09

Abstract excerpt

<title>Abstract</title> <p>Individual patient data (IPD) enable survival analysis and meta-analysis across multicenter studies, supporting evidence-based decision-making and trial design. However, openly available IPD remain scarce, and existing tools that reconstruct IPD from published Kaplan–Meier (KM) curves rely on labor-intensive, error-prone point extraction and exploit only limited subsets of reported info...

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Literature Corpus work: 4a414c8e-4cb5-51b0-a825-1314fc8e73d5
DOI: 10.21203/rs.3.rs-8789849/v1

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