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Exosomal microRNA-let-7b-5p Derived From Pancreatic Cancer Cells Possibly Promotes Insulin Resistance in C2C12 Myotube Cells by Targeting SLC6A15

2021-07-13

Abstract excerpt

<h4>Background: </h4> Cancers trigger systemic metabolic disorder usually associated glucose intolerance, which as initial apparent phenomenon. One of the features of pancreatic cancer (PC) metabolic reprogramming is the crosstalk between PC and peripheral tissues (skeletal muscle and adipose tissues), emphasized by insulin resistance (IR). In our previous study (Sci Rep. 2017;7(1):5384), we reported that mice pan...

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Literature Corpus work: 83b86a05-0ee4-5fa0-9a83-d5cd38e89de8
DOI: 10.21203/rs.3.rs-689703/v1

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