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Shared genetic foundation of the DHEAS pathway indicate similar extended childhoods in Neanderthals and modern humans

2026-06-27

Abstract excerpt

Adrenarche, the pre-pubertal rise in adrenal androgens, particularly dehydroepiandrosterone (DHEA) and its sulfated form DHEAS, is a critical driver of middle childhood cognitive and social development in modern humans. Compared to other apes, modern human adrenarche is more prolonged, with higher DHEAS levels. Whether this uniquely prolonged human adrenarche is a derived trait of Homo sapiens or has deeper homin...

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Literature Corpus work
83b0871a-9cb8-52d1-a886-5b6196f68713
DOI
10.64898/2026.06.25.734583
Open publication

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Shared genetic foundation of the DHEAS pathway indicate similar extended childhoods in Neanderthals and modern humansDOI 10.64898/2026.06.25.734583
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