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Article

Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution.

Chemical senses - 1 Sept 2015

Hoover Kara C, Gokcumen Omer, Qureshy Zoya, Bruguera Elise, Savangsuksa Aulaphan, Cobb Matthew, Matsunami Hiroaki

Abstract excerpt

Allelic variation at 4 loci in the human olfactory receptor gene OR7D4 is associated with perceptual variation in the sex steroid-derived odorants, androstenone, and androstadienone. Androstadienone has been linked with chemosensory identification whereas androstenone makes pork from uncastrated pigs distasteful ("boar taint"). In a sample of 2224 individuals from 43 populations, we identified 45 OR7D4 single...

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Identifiers

PMID: 26072518
DOI: 10.1093/chemse/bjv030
PMCID: PMC4635637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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