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Non-invasive detection of bladder cancer through the analysis of driver gene mutations and aneuploidy

2017-10-16

Abstract excerpt

Current non-invasive approaches for bladder cancer (BC) detection are suboptimal. We report the development of non-invasive molecular test for BC using DNA recovered from cells shed into urine. This “UroSEEK” test incorporates assays for mutations in 11 genes and copy number changes on 39 chromosome arms. We first evaluated 570 urine samples from patients at risk for BC (microscopic hematuria or dysuria). UroSEEK...

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Literature Corpus work
8368dffa-014a-5d9c-8ed0-3a72a450e50c
DOI
10.1101/203976
Open publication

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Non-invasive detection of bladder cancer through the analysis of driver gene mutations and aneuploidyDOI 10.1101/203976
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