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Melanin regulates mitochondrial dynamics, metabolism and inflammatory signaling to protect the retina

2026-05-17

Abstract excerpt

Albino individuals are clinically recognized to exhibit heightened susceptibility to light-induced retinal injury, yet the cellular and metabolic mechanisms underlying this vulnerability remain poorly defined. Here, we investigated whether retinal pigment epithelium (RPE) pigmentation governs mitochondrial structure, metabolism, and inflammatory responses that ultimately determine retinal resilience to blue light...

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Literature Corpus work
833ca274-7b43-5a14-9e4b-f973a119b8ae
DOI
10.64898/2026.05.15.724948
Open publication

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Melanin regulates mitochondrial dynamics, metabolism and inflammatory signaling to protect the retinaDOI 10.64898/2026.05.15.724948
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