Article

Autoimmune Lymphoproliferative Syndrome (Alps) Disease and Alps Phenotype: Are They Two Distinct Entities?

2022-02-17

Abstract excerpt

<title>Abstract</title> <p>Introduction Autoimmune Lymphoprolypherative Syndrome (ALPS) is an inherited disorder of lymphocyte homeostasis classically due to mutation of FAS, FASL, and CASP10 genes (ALPSFAS/CASP10). In spite of recent progress, about one third of ALPS patients does not carry classical mutations and still remains gene orphan (ALPS-U, undetermined genetic defects). Objective The aims of the prese...

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Literature Corpus work: 832fc015-75c3-5f23-9822-6c957622d977
DOI: 10.21203/rs.3.rs-1284777/v1

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