Article
Autoimmune lymphoproliferative immunodeficiencies (ALPIDs): A proposed approach to redefining ALPS and other lymphoproliferative immune disorders.
The Journal of allergy and clinical immunology - 1 Jan 2024
Magerus Aude, Rensing-Ehl Anne, Rao V Koneti, Teachey David T, Rieux-Laucat Frederic, Ehl Stephan
Abstract excerpt
Chronic nonmalignant lymphoproliferation and autoimmune cytopenia are relevant manifestations of immunohematologic diseases of childhood. Their diagnostic classification is challenging but important for therapy. Autoimmune lymphoproliferative syndrome (ALPS) is a genetically defined inborn error of immunity combining these manifestations, but it can explain only a small proportion of cases. Diagnostic categories...
Topics
- Humans
- Autoimmune Lymphoproliferative Syndrome
- Anemia, Hemolytic, Autoimmune
- Common Variable Immunodeficiency
- Immune System Diseases
- Phenotype
- fas Receptor
- Lymphoproliferative Disorders
- Autoimmune Diseases