Article

Mixed ctDNA dynamics and decreased detection rates in early-stage lung cancer patients during radiation treatment

2024-06-05

Abstract excerpt

Quantification and detection of circulating tumor DNA (ctDNA) has been used to identify the presence of cancers. Ablative radiation therapy kills tumor cells to reduce tumor burden and it follows that these dying tumor cells could lead to increased ctDNA abundance. We carried out deep, error-corrected sequencing of cell-free DNA collected serially from 12 stage I, and 2 stage II/III non-small cell lung cancer (NSC...

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Literature Corpus work: 830b4060-1522-5f7d-8e71-71ccef305922
DOI: 10.1101/2024.06.03.24308298

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