Article

Cellular origin and therapeutic potential of SERPINA3N in ischemic stroke

2026-07-29

Abstract excerpt

Murine serine protease inhibitor clade A member 3N (SERPINA3N) and its human homolog SERPINA3 are injury-associated molecules induced in virtually all neurological conditions including ischemic stroke. Clinically, SERPINA3 is elevated in stroke patients, correlating with severe brain pathology and worse neurological outcomes. Yet, the exact cellular sources and therapeutic value of SERPINA3N/SERPINA3 in the ischem...

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Literature Corpus work: 461c29c7-85ba-5084-a40b-5db893a75863
DOI: 10.64898/2026.07.27.741013

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